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= SICKLE CELL ANEMIA =

Name of Gene: Hemoglobin, beta Gene Symbol: HBB

What is Sickle Cell Anemia?
==Sickle cell anemia is a disorder that affects hemoglobin. Hemoglobin is located in the red blood cell. Red blood cells send oxygen throughout your body and are very important in keeping humans alive. People that have this disorder have molecules called Hemoglobin S. Hemoglobin S can change the shape of the round blood cells, to a stiff banana shaped blood cell. ==

What are symptoms of Sickle Cell Anemia?[[image:http://www.aurorahealthcare.org/healthgate/images/si55551158.jpg]]
**When the red blood cells sickle in your body, it causes many symptoms of anemia. Some symptons of sickle cell anemia can vary from certain individual, to mild symptons to severe symptons.The main symptoms of sickle cell anemia are, shortness of breath, fatigue,headaches, coldness in hands and feet and also delayed growth in children with this disease. When the red blood cells are being broken down so fast it causes yellowing of the eyes, and skin. At times there can be a spike in pain. The reason for the pain is the thin inflexible red sickled blood cells. When these stiff misshaped blood cells get stuck in small blood vessels it can deprive organs or certain parts of the body of oxygen therefor causing extreme pain. When oxygen cannot be distributed throughout the body there can be damage to not only to organ but to the lungs, kidneys, spleen, and even the brain. Another one of the most serious symptoms is high blood pressure in the blood vessels that supply oxygen to the lungs. This is called pulmonary hypertension, and occurs in one third of adults that have this disease and can ultimately lead to a heart attack.**

How can you Prevent Sickle Cell Anemia?
==Sickle cell anemia is a genetically linked inherited. Inheritance cannot be prevented, but can be predicted. Screening is recommended for individuals in high risk populations in the United States. African Americans and Hispanic American have the highest risk ==



== Sickle cell anemia is recessive so if two carriers had a child there is a 25% chance that the baby will be afflicted, 50% chance that the baby will be a carrier, and there is a 25% chance the baby will not be affected. ==

What population does Sickle Cell anemia affect?
==Sickle cell anemia occurs in Individuals who ancestors lived in Sub-Saharan Africa, Middle East, India or the Mediterranean region, and are the most likely to have the trait. ==

What is the Life expectance of someone with sickle cell anemia?
==Life Expectancy for an individual that has Sickle Cell anemia varies from 42 years of age for males and 48 years of age for women. ==

Famous people that have sickle cell anemia
T-BOz(TLC) Tiki Barber, Former Football Player (New York Giants) Miles Davis (Jazz Musican)

Sickle Cell Anemia is autosomal beacuse the gene does not seperate.